Chemical communication threatened by endocrine-disrupting chemicals.
نویسندگان
چکیده
منابع مشابه
Chemical communication threatened by endocrine-disrupting chemicals.
Communication on a cellular level--defined as chemical signaling, sensing, and response--is an essential and universal component of all living organisms and the framework that unites all ecosystems. Evolutionarily conserved signaling "webs," existing both within an organism and between organisms, rely on efficient and accurate interpretation of chemical signals by receptors. Therefore, endocrin...
متن کاملEndocrine disrupting chemicals
The idea that xenobiotic chemicals could inappropriately modlate the endocrine system thereby causing detrimental effects n wildlife and humans was first proposed 20 years ago at the atershed Wingspread Conference [1,2]. These endocrine disruptng chemicals (EDCs) have long been controversial, with a great eal of discussion raging in the scientific literature. Much of this ontroversy has centere...
متن کاملThe challenge posed by endocrine-disrupting chemicals.
Rapid regulatory developments in the area of environmental endocrine disruption present a series of potential problems that are identified and illustrated with examples taken from the recent literature. A list of priorities is provided, including the need for additional epidemiological and wildlife studies, the derivation of a coordinated testing strategy, agreement on the toxicities expected o...
متن کاملChemical Genomic Study of Endocrine Disrupting Chemicals in Metabolic Pathways
Endocrine disrupting activities in industrial chemicals have been a serious problem, because they are distributed broadly, they are active at very low concentrations, and some of them are difficult to detoxify. Moreover, only a small number of active chemicals are known, while most chemicals have not been examined yet. To reduce the number of examinations required for unknown chemicals, some co...
متن کاملCryptorchidism and endocrine disrupting chemicals
Prospective clinical studies have suggested that the rate of congenital cryptorchidism has increased since the 1950s. It has been hypothesized that this may be related to environmental factors. Testicular descent occurs in two phases controlled by Leydig cell-derived hormones insulin-like peptide 3 (INSL3) and testosterone. Disorders in fetal androgen production/action or suppression of Insl3 a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2004
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.6455